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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

The 96-h LC50 for fish was determined to be 4.2 mg/L (Markert & Weigand, 1984). The study was conducted with the zebra fish (Danio rerio) equivalent to OECD guideline 203 and in compliance with GLP.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
4.2 mg/L

Additional information

Different 96-h LC50 values obtained for several fish species have been published. These data are only available as secondary literature or as short abstract and their reliabilities are therefore not assignable. As the tested AOS has not been specified, the length of the C chains is unknown. As longer-chain AOS are more toxic than those with shorter alkyl chains (Little, 1993), the observed toxicity to fish increases with the alkyl chain length in the range between C12and C18.It is thus necessary for a reliable hazard assessment to consider the chain length of the test compound. As two guideline studies have been performed with AOS of C14-16 chain length, the more sensitive study has been set as key study. Both studies have been conducted with zebra fish (Danio rerio) equivalent to OECD guideline 203 and in compliance with GLP resulting in 96-h LC50 values of 4.2 mg/L and 12.2 mg/L.