Registration Dossier
Registration Dossier
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EC number: 500-070-7 | CAS number: 30583-72-3
Endpoint summary
Administrative data
Description of key information
The test substance, 4,4'-Isopropylidenedicyclohexanol, oligomeric reaction products with 1-chloro-2,3-epoxypropane , was evaluated for eye and skin irritation potential in in vitro tests O.E.C.D. 439 and O.E.C.D. 437 and in rabbit eye (O.E.C.D. 405) and skin (O.E.C.D. 404) irritation studies performed under the GLPs.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The test substance, 4,4'-Isopropylidenedicyclohexanol, oligomeric reaction products with 1 -chloro-2,3 -epoxypropane, was not an eye irritant in the in vitro O.E.C.D. 437 BCOP test and the O.E.C.D. test guideline 402 rabbit eye irritation study.
The test substance was not a skin irritant in the O.E.C.D test guideline 404 rabbit study. Furthermore, the test substance was not irritating to the skin of rats in an O.E.C.D.402 Acute Dermal study with a prolonged exposure time of 24 hours.
Justification for classification or non-classification
Classification of the test substance as an irritant is not required based upon the outcome of the required in vitro and animal tests.
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