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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Principles of method if other than guideline:
no data
Dissociating properties:
25 °C
The dissociation constant of p-cresol is 10.26 at 25°C.
Executive summary:

The dissociation constant of p-cresol is 10.26 at 25°C.

Description of key information

The dissociation constant of p-cresol is 10.26 at 25°C.

Key value for chemical safety assessment

pKa at 20°C:

Additional information

There is only a value at 25°C available. It is assumed that change in pKa is not a very sensitive function of temperature, and the value at 25°C is therefore assigned to a temperature of 20°C.

p-Cresol is a weak acid. The pKa value of 10.26 indicate that at environmentally relevant pH values (5 - 9) the substance is largely non-dissociated.