Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Melamine is a stable molecule.

Melamine is hydrolyzed only by mineral acid or inorganic alkali. Hydrolysis proceeds stepwise, with loss of one, two, or all three amino groups, i.e. producing ammeline, ammelide and cyanuric acid.

Melamine is not readily or inherently biodegradable. Biodegradation, also stepwise, to cyanuric acid and lastly to CO2 and NH4+ can occur in waste water treatment plants with adapted microorganisms.

No bioaccumulation is expected, as the determined bioconcentration factors in fish are <1 (only at 0.2 ppm the BCF = 3.8).

Based on the low n-octanol/water partition coefficient also the adsorption to soil or sediment is expected to be low, i.e. in the range of 1.1 to 1.5.

Some monitored data in the environment and wildlife are available from surveys in Japan, performed in earlier years.