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Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1999
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Remarks:
The tests was conducted based on OECD-GLP standards and OECD test guidelines. However, the Ministry of the Environment of Japan suggest confirmation of the results since the test was conducted in 1999 and some of the tests conducted before 2002 were performed using a dispersant.
Qualifier:
according to guideline
Guideline:
OECD Guideline 211 (Daphnia magna Reproduction Test)
Deviations:
not specified
GLP compliance:
yes
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Daphnia magna
Test type:
not specified
Water media type:
freshwater
Limit test:
no
Total exposure duration:
21 d
Reference substance (positive control):
not specified
Key result
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
0.069 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
reproduction
Key result
Duration:
21 d
Dose descriptor:
EC50
Effect conc.:
0.096 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
reproduction
Validity criteria fulfilled:
not specified
Conclusions:
The 21day-NOEC for the test subtance BHT in Daphnia magna was 0.069
Executive summary:

A Daphnia magna reproduction test was conducted by the Ministry of the Environment in Japan based on OECD GLP-standards and OECD guideline 211. The 21day-NOEC of BHT in Daphnia magna was 0.069 mg/L and the 21day-EC50 was 0.096 mg/L.

Description of key information

The 21day-NOEC of BHT in Daphnia magna was 0.069 mg/L and the 21day-EC50 was 0.096 mg/L

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.069 mg/L

Additional information

Key study: Test method according to OECD guideline 211: The 21day-NOEC of BHT in Daphnia magna was 0.069 mg/L and the 21day-EC50 was 0.096 mg/L.