Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-881-4 | CAS number: 128-37-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Remarks:
- Internationally accepted method, EPI-Suite, EPA (USA)
- Principles of method if other than guideline:
- Calculation by EPI-Suite, EPA (USA) / KOWWIN v1.67 estimate
- GLP compliance:
- no
- Type of method:
- other: estimated by calculation
- Partition coefficient type:
- octanol-water
- Analytical method:
- other: Estimated by calculation
- Key result
- Type:
- log Pow
- Partition coefficient:
- 5.03
- Remarks on result:
- other: EPISuite calculation: no data provided on temperature and pH to be included under "Results and discussions".
- Conclusions:
- The estimated log Pow is 5.03 (EPI-Suite, KOWWIN v1.67 estimate).
- Executive summary:
The estimated log Pow is 5.03 (EPI-Suite, KOWWIN v1.67 estimate).
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Data referenced in the article is taken from literature. Although the methodology to measured the log Pow is not included in the article, the values are taken into account for the weight of evidence analysis.
- Principles of method if other than guideline:
- No data provided on the test method.
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Partition coefficient type:
- octanol-water
- Analytical method:
- not specified
- Key result
- Type:
- log Pow
- Partition coefficient:
- >= 5.11 - <= 5.2
- Remarks on result:
- other: Publication: no data provided on temperature and pH to be included under "Results and discussions".
- Conclusions:
- The log Pow is 5.11-5.20.
- Executive summary:
The log Pow is 5.11-5.20.
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- EPI-Suite experimental database (Ref: TSCATS)
- Principles of method if other than guideline:
- No data provided on the test method.
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Partition coefficient type:
- octanol-water
- Analytical method:
- not specified
- Key result
- Type:
- log Pow
- Partition coefficient:
- 5.1
- Conclusions:
- The log Pow is 5.10 (EPI-Suite, experimental database).
- Executive summary:
The log Pow is 5.10 (EPI-Suite, experimental database).
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- The method is well described and was used for several substances. The technique was checked in some substances by a potentiometric method.
- Reason / purpose for cross-reference:
- reference to same study
- Principles of method if other than guideline:
- Partition coefficient determined spectrophotometrically in octanol-water solution at 37ºC.
- GLP compliance:
- not specified
- Type of method:
- other: Spectrophotometric method.
- Partition coefficient type:
- octanol-water
- Analytical method:
- photometric method
- Type:
- Pow
- Partition coefficient:
- 14 700
- Temp.:
- 37 °C
- Remarks on result:
- other: pH independent
- Type:
- log Pow
- Partition coefficient:
- 4.17
- Temp.:
- 37 °C
- Remarks on result:
- other: pH independent
- Conclusions:
- The partition coefficient (octanol/water) of BHT was 14700.
- Executive summary:
The partition coefficient of BHT was determined by a spectrophotometric method. The technique was checked on several compounds for which the partition coefficient was determined by a potentiometric technique (phenol, thymol, p-cresol, propyl-paraben). The partition coefficient (octanol/water) of BHT at 37ºC was 14700, the log Pow was 4.17.
Referenceopen allclose all
EPI-Suite experimental database: no data provided on temperature and pH to be included under "Results and discussions".
Description of key information
Based on the experimental results referenced in a scientific article the log Pow is 4.17 -5.20.
Based on the estimated data using EPI-Suite, the log Pow is 5.03.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 5.2
Additional information
Weight of evidence: Experimental results referenced in scientific articles and estimated results using EPI-Suite (EPA, USA).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
