Registration Dossier

Administrative data

Description of key information

No respiratory irritation was noted during any of the inhalation exposures with DME.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no study available

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

This substance is a gas and guideline testing for irritation or corrosion is not feasible.  No skin or eye irritation or corrosion or respiratory irritation was noted during any of the inhalation exposures.


Justification for selection of skin irritation / corrosion endpoint:
Study is technically not feasible because the test substance is a gas.

Justification for selection of eye irritation endpoint:
Study is technically not feasible because the test substance is a gas.

Justification for classification or non-classification

This substance is a gas and guideline testing for irritation and corrosion is not feasible.  No skin or eye irritation or corrosion or respiratory irritation was noted during any of the inhalation exposures. The substance does not need to be classified for irritation according the EU Directive 67/548/EEC and EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.