Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
Arniot LG
Year:
1932
Bibliographic source:
Presse Med., 40:300-302 (CA27:7819).

Materials and methods

GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
mouse

Administration / exposure

Route of administration:
intraperitoneal
Doses:
5 mg/kg

Results and discussion

Any other information on results incl. tables

The test substance is less efficient than diethylether as an anesthetic in animals. It does however have both vasodilator and hypotensor effects. Intraperitoneal doses of 5 mg/kg DME produced reversible anethesia in mice.

Applicant's summary and conclusion