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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Limited data.

Data source

Reference
Reference Type:
publication
Title:
Triaryl/alkyl phosphate residues in human adipose autopsy samples from six Ontario municipalities.
Author:
LeBel GL, Williams DT, Berard D
Year:
1989
Bibliographic source:
Bull. Environ. Contam. Toxicol. 43(2), 225-230

Materials and methods

Type of study / information:
Type of experience: other: Determination of exposure
Principles of method if other than guideline:
see below
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Triphenyl phosphate
EC Number:
204-112-2
EC Name:
Triphenyl phosphate
Cas Number:
115-86-6
Molecular formula:
C18H15O4P
IUPAC Name:
triphenyl phosphate

Results and discussion

Results:
Biomonitoring Species: human Method: Samples of adipose tissue from the greater omentum were obtained at autopsies of people residing in six Ontario, Canada municipalities. Each was analyzed for presence of 13 trialkyl/aryl phosphates, including TPP. No measurable TPP (detection limit 1 ng/g) was found in any fat samples.

Applicant's summary and conclusion

Conclusions:
No measurable TPP (detection limit 1 ng/g) was found in any fat samples.
Executive summary:
Biomonitoring
Species: human
Method: Samples of adipose tissue from the greater omentum were obtained at autopsies of people residing in six Ontario, Canada municipalities. Each was analyzed for
presence of 13 trialkyl/aryl phosphates, including TPP.

No measurable TPP (detection limit 1 ng/g) was found in any fat samples.