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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
GLP compliance:
not specified
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge (adaptation not specified)
Duration of test (contact time):
28 d
Initial conc.:
100 mg/L
Based on:
test mat.
Parameter followed for biodegradation estimation:
other: BOD
Parameter:
other: BOD
Value:
>= 83 - <= 94
Sampling time:
28 d
Parameter:
BOD5
The test was conducted in accordance with "Biodegradation test of chemical 
substance by microorganisms etc." stipulated in the Order Prescribing the 
Items of the Test Relating to the New Chemical Substance (1974, Order of 
the Prime Minister, the Minister of Health and Welfare, the Minister of 
International Trade and Industry No. 1). This guideline corresponds to "301C, 
Ready Biodegradability: Modified MITI Test (I)" stipulated in the OECD Guidelines
for Testing of Chemicals (1981)
Interpretation of results:
readily biodegradable
Conclusions:
Under the conditions used TPP can be considered readily biodegradable
Executive summary:

The test was conducted in accordance with "Biodegradation test of chemical substance by microorganisms etc." stipulated in the Order Prescribing the Items of the Test Relating to the New Chemical Substance (1974, Order of the Prime Minister, the Minister of Health and Welfare, the Minister of International Trade and Industry No. 1). This guideline corresponds to "301C, Ready Biodegradability: Modified MITI Test (I)" stipulated in the OECD Guidelines for Testing of Chemicals (1981).

As a biodegradation of 83 - 94% is found within 28 d the substance can be considered as "readily biodegradable".

Description of key information

The test was performed according to "301C, Ready Biodegradability: Modified MITI Test (I)" stipulated in the OECD Guidelines for Testing of Chemicals (1981).

As a biodegradation of 83 - 94 % is found within 28 d the substance can be considered as "readily biodegradable".

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

According to OECD guideline 301 "The 10-d window concept does not apply to the MITI method".