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EC number: 204-658-1
CAS number: 123-86-4
- using three skin samples from the same donor the following
permeability constant was determined for n-butyl acetate: 1.98 +/- 0.25
g/m2*h (un-normalized) and 1.58 +/- 0.09 g/m2*h
(normalized with respect of the mean permeability constant of [3H] water)
- 1.6 +/- 0.1 g/m2*h correspond to 1.8 +/+ 0.1 cm3/m2*h
Skin permeability of n-butyl acetate was investigated in vitro
using a Franz-Diffusion cell and viable skin from female human
donors. The permeability constant for n-butyl acetate was 1.6
+/- 0.1 g/m2*h (1.8 +/+ 0.1 cm3/m2*h),
indicating that the test item has only a low tendency to penetrate the
skin (Ursin et al., 1995).
The study is reliable with restrictions (RL2).
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