Registration Dossier
Registration Dossier
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EC number: 931-330-1 | CAS number: 69227-24-3
Endpoint summary
Administrative data
Description of key information
Bioaccumulation: aquatic / sediment
On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, the BCF value of the test chemical can be expected to be in range of 29 to 190, respectively. Thus, as this value does not exceed the bioconcentration threshold of 2000 indicating that the test chemical is not expected to bioaccumulate in the food chain.
Additional information
Bioaccumulation: aquatic / sediment
Data available for its read across chemicals has been reviewed to determine the bioaccumulation potential of the test chemical. The studies are as mentioned below:
Bioaccumulation study was conducted on test organism Cyprinus carpio for 31 d for evaluating the bioconcentration factor (BCF value) of test chemical. The study was performed according to other guideline "Bioaccumulation test of a chemical substance in fish or shellfish" provided in "the Notice on the Test Method Concerning New Chemical Substances", respectively. Cyprinus carpio was used as a test organism for the study. Test chemical was prepared in HCO-40. Test chemical nominal conc. used for the study was 0.0848 mg/l and 0.00848 mg/l, respectively. Range finding study involve the LC50(96h) > 15.3 mg/L on Rice fish (Oryzias latipes). TThe bioconcentration factor (BCF value) of test chemical on Cyprinus carpio was determined to be 150 L/Kg at a conc. of 0.0848 mg/l and 190 L/Kg at a conc. of 0.00848 mg/l, respectively, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is not expected to bioaccumulate in the food chain.
Another bioaccumulation study in fishwas conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculated using a water solubility of 226 mg/l and a regression-derived equation. The estimated BCF (bioaccumulation factor) valueof test chemical was determined to be 29 dimensionless, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is considered to be non-accumulative in aquatic organisms.
On the basis of the experimental studies of the test chemical and applying the weight of evidence approach, the BCF value of the test chemical can be expected to be in range of 29 to 190, respectively. Thus, as this value does not exceed the bioconcentration threshold of 2000 indicating that the test chemical is not expected to bioaccumulate in the food chain.
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