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Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study meets scientific standards

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Type of study / information:
Occupational exposure measurements
Endpoint addressed:
not applicable
Principles of method if other than guideline:
Monitoring of occupational exposure
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethyl vinyl ether
EC Number:
203-718-4
EC Name:
Ethyl vinyl ether
Cas Number:
109-92-2
Molecular formula:
C4H8O
IUPAC Name:
ethyl vinyl ether
Details on test material:
ethyl vinyl ether (EVE)

Method

Ethical approval:
not applicable
Details on study design:
Concentration in production and processing plants
Exposure assessment:
measured

Results and discussion

Results:
During 2000 to 2004, 45 measurements were carried out in the production and processing plants of BASF AG, Ludwigshafen. The values for production ranged from < 0.005 mg/m3 (< 0.002 ppm) to 120 mg/m3 (40 ppm) with a mean of 3.1 mg/m3 (1.0 ppm). The 90 and 95 % percentiles were at 0.97 mg/m3 (0.33 ppm) and 9.4 mg/m3 (3.1 ppm), respectively. The higher concentrations of up to 120 mg/m3 were observed during barreling, also depending on the season. For the processing plants, measurement values were all below 1 mg/m3.

Applicant's summary and conclusion

Conclusions:
Occupational exposure measurements at BASF AG.