Reaction products of D-Glucose, n-Butanol and C10-12 (even numbered) alcohols

Toxicity to microorganisms

Description of key information

EC0 (16 h, growth inhibition) = 5000 mg a.i./L for Pseudomonas putida (DIN 38412, part 8) (read-across)

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:

5 000 mg/L

Additional information

There are no data available on toxicity to microorganisms of Reaction products of D-Glucose, n-Butanol and C10-12 (even numbered) alcohols. However, there are reliable data for category member substances which are considered suitable for read-across based on a category approach. This read-across is in accordance with Regulation (EC) No. 1907/2006 Annex XI, 1.5 and justified in detail in the overall summary (IUCLID Chapter 6.1) and within the category justification attached in IUCLID Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was used for the assessment. Nevertheless, as it can be seen in the data matrix of the category justification in IUCLID Section 13 and the overall summary (IUCLID Chapter 6.1), all reliable data in the category support the hazard assessment of each category member by showing a consistent pattern of results.

Two studies investigated the effects of the category member and component of the substance D-Glucopyranose, oligomeric, C10-16-alkyl glycosides towards microorganisms. The tests were performed according to DIN 38412, part 27 and DIN 38412, part 8, respectively, with Pseudomonas putida (Henkel, 1995). No effects were observed resulting in an EC0 (30 min) of 500 mg a.i./L based on the respiration rate and an EC0 (16 h) of 5000 mg a.i./L based on the inhibition of growth. In conclusion, no effects of D-Glucopyranose, oligomeric, C10-16-alkyl glycosides towards microorganisms were found and can be expected.