Registration Dossier

Environmental fate & pathways

Additional information on environmental fate and behaviour

Administrative data

Endpoint:
additional information on environmental fate and behaviour
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The partition coefficient was obtained by the shake flask method according to the EU Method A.8.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report Date:
2000

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: EU Method A8.
Principles of method if other than guideline:
For the determination of the partition coefficient of 5-Methylisoxazole-4-carboxylic acid, the HPLCmethod was used.
The calibration of the method based on six reference substances with LogP values ranged from 0.3 to 1.8.
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

The calibration reads logk=0.0014 +0.686*LogP with a correlation coefficient of 0.983.

The test article showed a signal at 9.18min. The corresponding LogP value of 5 -Methylisoxazole-4 -carboxylic acid is 0.54.

Applicant's summary and conclusion

Conclusions:
5 -Methylisoxazole-4 -carboxylic acid LogP=0.54.