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EC number: 939-603-7 | CAS number: 1471316-72-9
In order to assess the toxicological behaviour of benzenesulfonic acid, di-C10-14-alkyl derivs., calcium salts, the available physico-chemical and toxicological data for it and its near calcium read across substances have been evaluated. The calcium sulfonate target substance is expected to be absorbed to a limited extent after oral exposure, based on its high molecular weight, its low water solubility and its high LogPow. Concerning the absorption after exposure via inhalation, as the chemical is considered to have a low vapour pressure, is highly lipophilic, has a high LogPow, and has a rather high molecular weight, it is clear, that the substance is poorly available for inhalation and will not be absorbed significantly.The calcium sulfonate target substance is also not expected to be absorbed following dermal exposure into the epidermis, due to its low water solubility and its fairly high molecular weight. Concerning its distribution in the body the calcium sulfonate target substanceis expected to be distributed into the intracellular compartment. The substance does not indicate a significant potential for accumulation, when taking into account the predicted behaviour concerning absorption and metabolism. The calcium sulfonate target substanceis expected to be extensively metabolised (metabolism by cytochrome P450 enzymes, followed by omega- and beta-oxidation and cleavage of the aromatic ring and desulfonation) andto be eliminated mainly via the urine and also via the bile.
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