Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

Short description of key information on bioaccumulation potential result: 
A qualitative judgement on the toxicokinetic behaviour based on physico-chemical characteristics is done following the recommendations of ECHA (ECHA Endpoint specific guidance, Chapter R.7c; section R.

Key value for chemical safety assessment

Bioaccumulation potential:
low bioaccumulation potential
Absorption rate - oral (%):
Absorption rate - dermal (%):
Absorption rate - inhalation (%):

Additional information

A qualitative judgement on the toxicokinetic behaviour was performed based on physico-chemical characteristics. Nitric acid is an inorganic substance and thus some physico-chemical characteristics (like the octanol/water partition coefficient) are not defined, limiting the possibilities of a qualitative assessment. Absorption factors of 100% are proposed for oral, inhalation and dermal absorption. For route-to-route extrapolation starting from oral data, an absorption factor of 50% is proposed as a worst-case assumption. Nitrate can be reduced to nitrite by both enteric bacteria and mammalian nitrate reductase activity. Nitric acid is not considered to have bioaccumulative potential as nitrate is highly soluble in water and rapidly excreted via the urine.