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EC number: 629-661-9 | CAS number: 83834-59-7
2-Ethylhexyl 4-methoxycinnamate had been injected into the left eye of 3 albino rabbits without rinsing, the left eye of another 3 albino rabbits were rinsed after 2 and 4 seconds, resp. Cornea, iris, and conjunctivae were examined. A slight irritation of the conjunctivae was observed during the few hours after application of pure 2-Ethylhexyl 4-methoxycinnamate. This irritation is manifested by the presence of some more capillaries injected into the eye treated than on the eye not treated. No effect, however small, could be detected 24 hours after application of the test substance. Based on these results, 2-Ethylhexyl 4-methoxycinnamate does not need to be classified as irritating according to the criteria outlined in regulation 1272/2008/EC.
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