Registration Dossier
Registration Dossier
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EC number: 629-661-9 | CAS number: 83834-59-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Test procedure conducted according to OECD guideline 209
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- GLP compliance:
- yes
- Analytical monitoring:
- no
- Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- Concentration of inoculum: 1 g/L referred to the dry weight
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 30 min
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorphenol
- Key result
- Duration:
- 30 min
- Dose descriptor:
- NOEC
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Remarks:
- respiration rate
Reference
No inhibition of respiration was observed up to a concentration of 1000 mg/L.
Description of key information
Toxicity to microorganisms: NOEC (respiration rate) is 1000 mg/L (according to OECD TG 209).
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
The inhibition of the respiration of domestic activated sludge was tested according to OECD TG 209 (GLP, reliability 1). The test concentrations were far above the water solubility limit of the test substance. The activated sludge was exposed for 30 minutes and the respiration rate was measured. The NOEC was above 1000 mg/L of the tested material.
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