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Ecotoxicological information

Toxicity to microorganisms

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Reference
Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
Test procedure conducted according to OECD guideline 209
Qualifier:
according to
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
yes
Analytical monitoring:
no
Test organisms (species):
activated sludge, domestic
Details on inoculum:
Concentration of inoculum: 1 g/L referred to the dry weight
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
30 min
Reference substance (positive control):
yes
Remarks:
3,5-Dichlorphenol
Key result
Duration:
30 min
Dose descriptor:
NOEC
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate

No inhibition of respiration was observed up to a concentration of 1000 mg/L.

Description of key information

Toxicity to microorganisms: NOEC (respiration rate) is 1000 mg/L (according to OECD TG 209).

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
1 000 mg/L

Additional information

The inhibition of the respiration of domestic activated sludge was tested according to OECD TG 209 (GLP, reliability 1). The test concentrations were far above the water solubility limit of the test substance. The activated sludge was exposed for 30 minutes and the respiration rate was measured. The NOEC was above 1000 mg/L of the tested material.