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Short-term toxicity to aquatic invertebrates

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Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
GLP compliance:
yes
Analytical monitoring:
yes
Details on test solutions:
The test was performed with an aqueous extract of the test substance (eluate).
Test organisms (species):
Daphnia magna
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
48 h
Nominal and measured concentrations:
Due to the analytical recovery rate of < 80 % the effective concentrations mentioned in this report are based on the median analytical recovery rate after 0 and 48 hours (0.0271 %).
Details on test conditions:
TEST SYSTEM
- Fill volume: 10 mL
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
- Biomass loading rate: 0.5 animals/mL

OTHER TEST CONDITIONS
- Photoperiod: 16 : 8 hours day-night regime
Duration:
48 h
Dose descriptor:
EC0
Effect conc.:
>= 0.027 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mobility
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 0.027 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mobility
Duration:
48 h
Dose descriptor:
EC100
Effect conc.:
> 0.027 mg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
test mat.
Basis for effect:
mobility
Details on results:
The test substance shows no inhibitory effect in the range of the water solubility.

Description of key information

Short-term toxicity to aquatic invertebrates: 48h-NOEC for Daphnia magna >= 0.0271 mg/L; 48h-EC50 >0.0271 mg/L (OECD TG 202).

Key value for chemical safety assessment

Additional information

The toxicity of the test substance to Daphnia magna was tested according to OECD TG 202 (GLP, reliability 1). The effective concentrations were based on the median analytical recovery after 0 and 48 hours. The 48h-EC50 was > 0.0271 mg/L (measured).