Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 271-516-3 | CAS number: 68583-51-7
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 01 Jun - 15 Aug 1976
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented study report which meets basic scientific principles.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 976
- Report date:
- 1976
Materials and methods
- Study type:
- study with volunteers
- Endpoint addressed:
- skin irritation / corrosion
- Principles of method if other than guideline:
- Human skin irritation study after single dermal application.
- GLP compliance:
- no
Test material
- Reference substance name:
- Decanoic acid, mixed diesters with octanoic acid and propylene glycol
- EC Number:
- 271-516-3
- EC Name:
- Decanoic acid, mixed diesters with octanoic acid and propylene glycol
- Cas Number:
- 68583-51-7
- Molecular formula:
- C21H44O6
- IUPAC Name:
- Waglinol 2/7680
Constituent 1
Method
- Type of population:
- other: patients from stationary admission of the dermatology department
- Subjects:
- - Number of subjects exposed: 120
- Sex:
52 males
59 females
- Other: only subjects without dermatosis or general dermal irritation were tested - Ethical approval:
- not specified
- Route of exposure:
- dermal
- Reason of exposure:
- intentional
- Exposure assessment:
- not specified
- Details on exposure:
- The test substance was applied on the back of the test subjects and occlusive covered with an adhesive plaster. After 24 h the plaster was removed.
- Examinations:
- 24, 48 and 72 h after application the skin reactions of all test subjects were observed. The evaluation of the skin reactions was according to the following scoring system (see Table 1).
Results and discussion
- Clinical signs:
- No clinical signs were observed for all test subjects during the study period.
- Results of examinations:
- SKIN EXAMINATION
All test subjects showed no skin reaction during the study period.
Applicant's summary and conclusion
- Conclusions:
- For the test substance good skin compatibility was observed in the present study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
