Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In a skin sensitisation study (LLNA) with magnesium sulphate itself, according to OECD 429, EU B.42 and OPPTS 870.2600 it was shown that the substance is not sensitising. All auricular lymph nodes of the animals of the experimental and control groups were considered normal in size. No macroscopic abnormalities of the surrounding area were noted in any of the animals.


Migrated from Short description of key information:
In a LLNA study with magnesium sulpate it is clear that the substance does not show any sensitising properties.

Justification for classification or non-classification

According to Directive 67/548/EC and the CLP Directive no classification of magnesium sulphate for sensitisation is required based on the reliable data present.