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EC number: 246-805-2 | CAS number: 25306-75-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Toxicity to reproduction
Administrative data
- Endpoint:
- toxicity to reproduction
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- QSARs for predicting effects relating to reproductive toxicity.
- Author:
- Cronin M.T.D. et all,
- Year:
- 2 008
- Bibliographic source:
- QSAR & Combinational Science 27: 91-100
- Reference Type:
- publication
- Title:
- A conceptual framework for predicting toxicity of reactive chemicals: Model for soft electrophilicity.
- Author:
- Schultz T.W. et all
- Year:
- 2 006
- Bibliographic source:
- SAR QSAR in Environmental research 17:413-428
- Reference Type:
- publication
- Title:
- Predicting Chemical Toxicity and Fate.
- Author:
- Tong W. et all,
- Year:
- 2 004
- Bibliographic source:
- CRC Press Boca Raton FL pp 285-314
Materials and methods
Test guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- QSAR Toolbox Version 2.2
Test material
- Reference substance name:
- Sodium O-ethyl dithiocarbonate
- EC Number:
- 205-440-9
- EC Name:
- Sodium O-ethyl dithiocarbonate
- Cas Number:
- 140-90-9
- Molecular formula:
- C3H6OS2.Na
- IUPAC Name:
- sodium O-ethyl dithiocarbonate
- Reference substance name:
- Sodium ethyl xanthate
- IUPAC Name:
- Sodium ethyl xanthate
- Reference substance name:
- Potassium O-ethyl dithiocarbonate
- EC Number:
- 205-439-3
- EC Name:
- Potassium O-ethyl dithiocarbonate
- Cas Number:
- 140-89-6
- IUPAC Name:
- potassium O-ethyl dithiocarbonate
- Reference substance name:
- Potassium ethyl xanthate
- IUPAC Name:
- Potassium ethyl xanthate
- Reference substance name:
- Proxan-sodium
- EC Number:
- 205-443-5
- EC Name:
- Proxan-sodium
- Cas Number:
- 140-93-2
- Molecular formula:
- C4H8OS2.Na
- IUPAC Name:
- sodium O-isopropyl dithiocarbonate
- Reference substance name:
- Sodium isopropyl xanthate
- IUPAC Name:
- Sodium isopropyl xanthate
- Reference substance name:
- Proxan-potassium
- EC Number:
- 205-441-4
- EC Name:
- Proxan-potassium
- Cas Number:
- 140-92-1
- IUPAC Name:
- O-isopropyl hydrogen dithiocarbonate
- Reference substance name:
- Sodium isobutyl xanthate
- IUPAC Name:
- Sodium isobutyl xanthate
- Reference substance name:
- Sodium O-isobutyl dithiocarbonate
- EC Number:
- 246-805-2
- EC Name:
- Sodium O-isobutyl dithiocarbonate
- Cas Number:
- 25306-75-6
- Molecular formula:
- C5H10OS2.Na
- IUPAC Name:
- sodium [(2-methylpropoxy)methanethioyl]sulfanide
Constituent 1
Constituent 2
Constituent 3
Constituent 4
Constituent 5
Constituent 6
Constituent 7
Constituent 8
Constituent 9
Results and discussion
Results: P0 (first parental generation)
Effect levels (P0)
- Dose descriptor:
- other:
- Basis for effect level:
- other: see 'Remark'
- Remarks on result:
- not measured/tested
- Remarks:
- Effect level not specifiedGeneration not specified (migrated information)
Overall reproductive toxicity
- Reproductive effects observed:
- not specified
Any other information on results incl. tables
DNA binding by OASIS: NO binding
DNA binding by OECD: NO binding
Estrogen Receptor Binding: NON binder: due to non-cyclic molecular structure and MW=<500
Remarks: Chemicals that have a molecular weight (MW) of less than 500, but do not possess a cyclic structure are reported to non binder to the receptor
Applicant's summary and conclusion
- Conclusions:
- DNA binding by OASIS: NO bindingDNA binding by OECD: NO bindingEstrogen Receptor Binding: NON binder: due to non-cyclic molecular structure and MW=<500Remarks: Chemicals that have a molecular weight (MW) of less than 500, but do not possess a cyclic structure are reported to non binder to the receptor
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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