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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Certain details lacking, but considered suitable to confirm similar results as would be expected for this substances
Study provided on similar substance to help build up a weight of evidence demonstrating potential for read-across between the xanthates

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
CCOHS, Registry of Toxic Effects of Chemical Substances, updated July 2010,
Author:
CCOHS, Registry of Toxic Effects of Chemical Substances
Year:
2010
Bibliographic source:
www.ccohs.ca
Reference Type:
secondary source
Title:
No information
Author:
Izmerov, N.F.et all
Year:
1982
Bibliographic source:
Moscow, Centr of International Projects, GKNT, vol.102

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 403 (Acute Inhalation Toxicity)
Deviations:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
Potassium O-butyl dithiocarbonate
EC Number:
212-808-2
EC Name:
Potassium O-butyl dithiocarbonate
Cas Number:
871-58-9
IUPAC Name:
potassium O-butyl dithiocarbonate
Constituent 2
Reference substance name:
Potassium n-butyl xanthate
IUPAC Name:
Potassium n-butyl xanthate
Test material form:
not specified

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Duration of exposure:
2 h
Control animals:
not specified

Results and discussion

Effect levels
Dose descriptor:
LC50
Effect level:
7 690 mg/m³ air
Clinical signs:
other:

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Executive summary:

Certain details lacking, but considered suitable to confirm similar results as would be expected for this substances


Study provided on similar substance to help build up a weight of evidence demonstrating potential for read-across between the xanthates