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Short-term toxicity to aquatic invertebrates

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Description of key information

EC50 (48h) = 49 mg/L (measured) for Daphnia magna (OECD 202, read across)

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
49 mg/L

Additional information

No studies investigating the short-term toxicity of l-Glutamic acid, N-coco acyl derivs., disodium salts (CAS No. 68187-30-4) to aquatic invertebrates are available. Thus, available data for the source substance l-Glutamic acid, N-coco acyl derivs., monosodium salts (CAS No. 68187-32-6) was used in a read across approach. The read across is considered valid as both substances are structurally identical (solely differing in the degree of deprotonation being di- and monosodium salts, respectively), which assume very similar physico-chemical properties resulting in identical environmental behavior and ecotoxicity.

The read across key study was performed according to GLP and OECD guideline 202 using Daphnia magna as test organism (Laus, 2011). Nominal concentrations between 2.2 and 100 mg/L were tested over a period of 48 h. Thus, a 48h-EC50 is determined to be 49 mg/L based on the measured test concentration. Due to the very high structural similarity, this result can also be considered for l-Glutamic acid, N-coco acyl derivs., disodium salts (CAS No. 68187-30-4).