Registration Dossier
Registration Dossier
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EC number: 204-661-8 | CAS number: 123-91-1
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
The partition coefficient is determined to be -0.42 at 20°C. The pH value is not relevant as the substance has no ionic character.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.42
- at the temperature of:
- 20 °C
Additional information
Several reliable literature sources reported the partition coefficient of 1-dioxane to be between -0.27 and -0.42. The Syracuse Research Coperation, Physical Properties Database and the GESTIS - Substance database reported the partition coefficient to be -0.27 based on experimental data, a patent of SUNTORY FLOWERS LIMITED (cited in REAXYS) reported the partition coefficient also to be -0.27, Perminova, Irina V.; Frimmel, Fritz H.; Kovalevskii, Dmitrii V.; Abbt-Braun, Gudrun; Kudryavtsev, Alexey V.; and Hesse, Sebastian, also cited in REAXYS, reported the partition coeffient to be -0.42.
Runar Collander and Roelof F. Rekker also reported the partition coeffient to be -0.42 and a calcukation done with KOWWIN v1.68 resulted a partition coefficient of -0.32.
They are all peer reviewed and authoritative secondary sources and regarded to be reliable for 1-dioxane. The value from Perminova, Irina V.; Frimmel, Fritz H.; Kovalevskii, Dmitrii V.; Abbt-Braun, Gudrun; Kudryavtsev, Alexey V.; and Hesse, Sebastian, cited in REAXYS, was chosen as key parameter for the partition coefficient.
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