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There is no data for the bioaccumulation or Kow of 2-methylbutane, so this value has been read across from n-pentane as this is the most protective value within the category. The potential bioaccumulation of n-pentane was calculated using the TGD guideline and the Log Kow. A log Kow for 2-methylbutane was not available but as n-pentane has a similar molecular structure to 2 -methylbutane and so is predicted to have similar physico-chemical characteristics, it was deemed suitable to used the Kow to read-across to 2-methylbutane. The BCF of n-pentane and thus 2 -methylbutane was calculated to be 171, based on a log Kow of 3.45. The BCF indicate that 2 -methylbutane has a low potential to bioaccumulate in the lipids of ecological receptors.