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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

NOEC (3 h) of ≥ 1000 mg/L for activated sludge microorganisms (OECD 209)

Key value for chemical safety assessment

Additional information

Since no studies investigating the toxicity to microorganisms of fatty acids, C16-18, isotridecyl esters (CAS 95912-88-2)are available for this endpoint, in accordance to Regulation (EC) No. 1907/2006 Annex XI, 1.5 a read across to the structurally related category member dodecyl oleate (CAS 36078-10-1) was conducted. The read-across substance is characterized by a similar fatty acid (C18 unsatd. compared to C16-C18 (target)) and a similar alcohol component (dodecanol compared to isotridecanol (target)). This read-across is justified in detail in the overall summary (IUCLID chapter 6.1) and within the category justification in IUCLID Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was used for the assessment. Nevertheless, as it can be seen in the data matrix of the category justification in section 13 and the overall summary, all reliable data in the category support the hazard assessment of each category member by showing a consistent pattern of results.

The study with the read-across substance dodecyl oleate was performed according to OECD 209 under GLP conditions (Brunswik-Titze, 2012). A limit test with a concentration of 1000 mg/L did not result in inhibition of respiration rate of activated sludge microorganisms (obtained from a sewage treatment plant treating predominantly domestic wastewater). An increase of respiration was observed in all three test vessels. Thus, a NOEC (3 h) of ≥ 1000 mg/L was derived.

Based on the available result from one structurally related read-across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5) which is characterized by a similar ecotoxicological profile and comparable structure, it can be concluded that fatty acids, C16-18, isotridecyl esters will not exhibit effects on activated sludge microorganisms.