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EC number: 242-362-4 | CAS number: 18479-58-8
Results of test
With the exception of two subjects that exhibited barely perceptible to moderate and marked erythema response, the test article produced barely perceptible to mild irritation with equivalent or less irritation seen for saline or vehicle controls.
The test material at a concentration of 20% was applied under occlusive patch to the upper backs of test subjects and was allowed to remain for 24 hours. Patches were applied Monday, Wednesday and Friday for a total of 9 applications. Patches were removed after approximately 24 hours and sites were graded for dermal irritation and sensitization. Following an approximately 2 week rest period, challenge patches of the test material were applied to previously untreated sites on the backs of test subjects. After 24 hours, sites were scored for dermal reactions and were re-evaluated at 48- and 72 -hours. A total of 99 subjects completed this study. Under the conditions of this study, the test material did not demonstrate a potential for eliciting dermal irritation or sensitization.
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