Registration Dossier

Administrative data

Description of key information

Acute dermal irritation/corrosion studies (OECD 404, EU Method B.4; OECD-Guideline 431; EC 440/2008: B.40.BIS; DRAFT: OECD Guideline “In Vitro Skin Irritation: Reconstructed Human Epidermis (RhE) Test Method”, Paris 9 September 2009 (3rd WNT circulation, Version 7.6; EC 761/2009: B.46): not irritant.
Eye irritation study (OECD 405, EU Method B.5; EPA OPPTS 870.2400):not irritant.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Skin irritation:

Before an in vivo test was performed, an in vitro skin corrosion test and an in vitro skin irritation test were performed. All studies were cinducted according to recent guidelines. The test substance was not irritating to the skin in either test.

Eye irritation:

Although there were some definitely injected blood vessels and obvious swellings of the conjunctivae with partial eversion of lids noted after administration of the test substance, as well as white mucous eye discharge, the test substance was not irritating to the eyes, based on the mean scores relevant for classification..


Effect level: empty Endpoint conclusion: Adverse effect observed

Justification for classification or non-classification

According to REGULATION (EC) No 1272/2008 "Resin 835 A" does not require classification for skin irritation and does not require classification for eye irritation.