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EC number: 911-238-8 | CAS number: -
The aim of the study was to investigate acute toxic effects of the test substance after a single peroral administration to rats.
Methods and investigations were performed in conformance with the OECD-Guideline 423,and theDirective2004/73/EC, method B.1 tris.
"VP Resin 835 A / Kat."was administered once as a suspension in an aqueous solution of 0.1 % Na-carboxymethylcellulose plus 0.1 % Tween 80, given orally via gavage to female Crl:CD(SD)IGS BR rats. The dosing was performed sequentially to groups of 3 animals per step using a starting dose of 2000 mg per kg body weight. The dose volume was 20 mL per kg body weight for all groups.
· Body weights: before administration, 7 and 14 days after the administration (p.a.).
· Clinical observations: at least once per day.
· Necropsy: The animals were sacrificed and necropsied 14 days p.a.
No. of animals
Presence of signs in life
Full recovery of the survivors
all animals gained weight in both weeks p.a.
Findings in life and post mortem indicate
no toxic effects present
> 2000 mg/kg body weight
According to Commission Directive 2001/59/EC"VP Resin 835 A / Kat." does not require classification for acute oral toxicity.
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