Registration Dossier

Administrative data

Description of key information

Acute oral toxicity (OECD 423, EU Method B.1 tris): LD50 >2000 mg/kg bw.
Acute dermal toxicity (OECD 402, EU Method B.3): >2000 mg/kg bw

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

Acute oral toxicity: The key study is a recent study (2005), performed according to actual guidelines. The test substance was administered in CMC/Tween 80 yielding a LD50 of >2000 mg/kg bw. There were no adverse effects noted in the animals.

Acute dermal toxicity: The key study is a recent study, performed according to actual guidelines. The LD50 was >2000 mg/kg bw and no adverse effects were noted in the animals.

Justification for classification or non-classification

According to REGULATION (EC) No 1272/2008 the test item does not require classification for acute oral or dermal toxicity.