Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
key study
Study period:
26 Sept 2011
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable, well-documented study report which meets basic scientific principles.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report Date:
2011

Materials and methods

Principles of method if other than guideline:
Calculation of log Pow from solubility in octanol (see section 4.9) and water (see section 4.8).
Type of method:
other: Calculation
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Study design

Analytical method:
other: chromatography and UV-vis spectrometry

Results and discussion

Partition coefficientopen allclose all
Type:
Pow
Partition coefficient:
9.12
Temp.:
21 °C
pH:
ca. 7
Type:
log Pow
Partition coefficient:
0.96
Temp.:
21 °C
pH:
ca. 7
Details on results:
The octanol and the water solubility were both determined at 21-22 °C.
It is not possible to enter a temperature range in the field above, therefore 21 °C was taken as the temperature value.

Any other information on results incl. tables

Calculation:

log Pow = log (c(n-octanol)/c(water))

(c: individual solubilities; see sections 4.8 and 4.9 and below).

Octanol solubility [µg/L]

 310

Water solubility [µg/L]

 34

Applicant's summary and conclusion

Conclusions:
The calculated log Pow of the test substance is 0.96.
Executive summary:

The log Pow of the test substance was calculated from the solubility in octanol (see section 4.9) and the solubility in water (see section 4.8). The calculated log Pow of the test substance is 0.96 at 21 -22°C.