Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-150-4 | CAS number: 1306-38-3
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- adult fish: sub(lethal) effects
- Data waiving:
- other justification
- Justification for data waiving:
- other:
Reference
Description of key information
Data waiving (other justification):
According to column 2 of REACH Annex IX, long-term assays are required if there is a need to further investigate the impacts on aquatic organisms. Due to its extremely low water solubility, it can be argued that cerium dioxide will not be bioavailable to aquatic organisms. Furthermore, in acute toxicity experiments with the bulk form of cerium dioxide, none of the tested species (i.e. fish, daphnids and algae) exhibited adverse impacts, with L/EC50 values all superior to 100 mg/L. A long-term experiment on daphnids is available, also showing no chronic effect. Due to the similar sensitivity between fish and daphnids during acute tests, due to the high insolubility of cerium dioxide, and in accordance with the REACH principle intended to limit vertebrate testing, the long-term assay on fish is not needed.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
