Registration Dossier
Registration Dossier
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EC number: 215-150-4 | CAS number: 1306-38-3
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- the study does not need to be conducted because the analytical method is not sensitive enough
- the study does not need to be conducted because the substance is insoluble
Reference
Description of key information
Data waiving (study technicall not feasible):
The study does not need to be conducted because:
- the analytical method is not sensitive enough,
- the substance is insoluble.
Key value for chemical safety assessment
Additional information
Dissociation is the reversible splitting of a substance into two or more chemical species, which may be ionic. In the case of cerium dioxide, due to a very low water solubility (< 0.123 µg/L at 20 °C for the bulk form, see IUCLID section 4.8), dissociation is not expected to occur under environmentally relevant pH. Furthermore, knowing that dissociation constant is the ratio of the concentrations of the different species in water at equilibrium, an analytical method sufficiently sensitive to discriminate between the different species shall be available. Here again, due to the insolubility, such a method does not exist for cerium dioxide. As a result, according to column 2 of REACH Annex IX, the study does not need to be carried out on the bulk form of cerium dioxide as there is no analytical method sensitive enough.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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