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Physical & Chemical properties

Melting point / freezing point

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Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
06-Jun-2015
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
GLP compliance:
no
Type of method:
thermal analysis
Remarks:
Differential Scanning Calorimetry
Melting / freezing pt.:
< -100 °C
Melting / freezing pt.:
< 173 K

Details:

 

The DSC diagrams show no melting/freezing temperature above –100°C.

 

Test

Melting temperature

1

<-100 °C

2

< -100 °C

Mean value

< -100 °C, < 173K

 

Conclusions:
A melting point of < -100°C (173 K) was determined in a reliable study conducted according to an appropriate test protocol. It was not conducted according to GLP.
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
28 Apr 2011
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
1.4.4.2 / 1.6.4.2
GLP compliance:
not specified
Type of method:
thermal analysis
Remarks:
Differential Scanning Calorimetry
Melting / freezing pt.:
-53.5
Remarks on result:
other: if cooling to a temperature below -100°C (173K)

Results:

The DSC diagrams show an exothermic process beginning at about -95°C (approximately 178K). This can be interpreted as a kind of crystallization process, so that a solid phase results.

The solid phase melts with an endothermic reaction and an onset temperature at -53.5°C (219.7K).

Conclusions:
A melting point of -53.5°C was determined in a reliable study conducted according to an appropriate test protocol. It was not conducted according to GLP.

Description of key information

<-100°C at 1013 hPa (measured)

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-100 °C

Additional information

A melting point value of <-100°C was determined by differential scanning calorimetry according to OECD test guideline 102. This is supported by measured values of -53.5°C obtained from another study and <-50°C obtained from a secondary source (company data).The supporting results are in good agreement with the key study.