Registration Dossier
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EC number: 203-872-2 | CAS number: 111-46-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Readily biodegradable (according to OECD criteria).
Key value for chemical safety assessment
Additional information
Diethylene glycol was shown to meet the ready biodegradability criteria in a carbon dioxide evolution test according to OECD 301B (BASF, 1995). It should also be considered that diethylene glycol is generally used as a reference substance in biodegradability screening tests.
In addition to this information, the biodegradability of diethylene glycol is assessed in the read-across approach of 'ethylene glycol and higher glycols' (mono-, di-, tri-, tetra- and pentaethylene glycol). Within this read-across, all evidence indicates that the ethylene glycols are readily biodegradable. In case of mono-ethylene glycol (EG) a very rapid biodegradation was detected in the DOC Die Away Test according to OECD 301A (BASF, 1996). The time window of the degradation phase is approx. 3 days. With the same test method it could be shown that tetra-EG is degraded within a time window of approx. 9 days (BASF, 1995). For tri-EG, data from a MITI test according to OECD 301C showed results that also indicate the readily biodegradability (MITI, 1992). In this study biodegradation varied between 25% and 92% degradation after 28 days.
In conclusion, the evaluation of the biodegradability of the five short chain ethylene glycols can be derived from numerous different studies. Summarizing all available data it can be concluded that the complete members of the group are readily biodegradable.
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