Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 207-312-8 | CAS number: 461-58-5
Table 2: Individual scores awarded to the ocular lesions elicited by Dicyandiamid
After 24 hours
After 48 hours
After 72 hours
After 7 days
In an acute eye irritation study according to FDA-standards, 0.1 ml of Dicyandiamid was instilled into the eyes of six albino rabbits (New Zealand White strain). Eyes were not washed afterwards. Animals then were observed after 24, 48, 72 hours and 7 days. Irritation was scored by the method of US EPA 560/6-82-001.
Under the experimental conditions employed, Dicyandiamid produced slight corneal damage, slight irititis and moderate redness and swelling of the conjunctivae in one rabbit and slight redness of the conjunctivae in the other five rabbits. During the seven-day observation period these eye lesions recovered incompletely so that at the seventh day reading slight redness of the conjunctivae was still observed in two out of six rabbits.
According to the FDA-standard the test material is not considered to be an eye irritant.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again