Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Adequacy of study:
supporting study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1995

Materials and methods

GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Hydrogen peroxide
EC Number:
231-765-0
EC Name:
Hydrogen peroxide
Cas Number:
7722-84-1
Molecular formula:
H2O2
IUPAC Name:
hydrogen peroxide
Details on test material:
IUCLID4 Test substance: other TS

TS-Freetext:
35% hydrogen peroxide

Test animals

Species:
mouse
Sex:
male/female

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Any other information on results incl. tables

RS-Freetext:
In a preliminary toxicity testing preceeding a cytogenetic
study, i.p. injection of 2000 mg/kg hydrogen peroxide (8%
solution, 25 ml/kg) caused convulsions followed by mortality
in 5/13 males and 7/13 females.  The same dose given in two
doses of 4 or 5% solutions killed 2/2 or 4/6 males,
respectively (but none of the females).

Applicant's summary and conclusion