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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Adequacy of study:
supporting study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1995

Materials and methods

GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Hydrogen peroxide
EC Number:
231-765-0
EC Name:
Hydrogen peroxide
Cas Number:
7722-84-1
Molecular formula:
H2O2
IUPAC Name:
hydrogen peroxide
Details on test material:
IUCLID4 Test substance: other TS

TS-Freetext:
35% hydrogen peroxide

Test animals

Species:
mouse
Sex:
male/female

Administration / exposure

Route of administration:
intraperitoneal

Results and discussion

Any other information on results incl. tables

RS-Freetext:
In a preliminary toxicity testing preceeding a cytogenetic
study, i.p. injection of 2000 mg/kg hydrogen peroxide (8%
solution, 25 ml/kg) caused convulsions followed by mortality
in 5/13 males and 7/13 females.  The same dose given in two
doses of 4 or 5% solutions killed 2/2 or 4/6 males,
respectively (but none of the females).

Applicant's summary and conclusion