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Long-term toxicity to aquatic invertebrates

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Description of key information

A reliable guideline-study on the chronic toxicity of hydrogen peroxide to Daphnia magna is available that resulted in a NOEC of 0.63 mg/L.

Key value for chemical safety assessment

Additional information

Data are available from the public domain on a reproduction test in Daphnia magna (Meinertz et al. 2008) conducted according to ASTM guidance (E 1193-97). Daphnids were exposed under flow-through conditions for 21 days to a range of concentrations, i.e., 0.32, 0.63, 1.25, 2.5 and 5.0 mg/L. Survival and reproduction of parent generation was not affected at concentrations up to and including 1.25 mg/L. Body length of adult water flea was statistically significantly reduced after 21 days at 0.32 mg/L compared to the control, however, the difference was so small that it is considered not biologically meaningful. Therefore, a NOEC of 0.63 mg/L is considered under the test conditions.

A further supporting long-term test with invertebrates is available from public literature addressing potential adverse effects of Fenton’s reagent (hydrogen peroxide in combination with ferrous ion) on zebra mussel Dreissena polymorpha (Klerks and Fraleigh, 1991). In the 56-day flow-through test (11 °C; pH 8.25; average concentrations hydrogen peroxide/total iron: 0.79/0.33, 1.62/0.61 and 4.47/1.53 mg/L), the NOECmortality for zebra mussel was 1.62 mg/L.