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The acute aquatic toxicity of hydrogen peroxide to fish, invertebrates and aquatic algae has been investigated in a number of valid assays and the following (lowest) EC50 values have been derived from acute studies: 16.4 mg/L in fish, 2.4 mg/L in daphnia and 1.38 mg/L in algae (marine diatoms). It appears that algae represent the most sensitive species with regard to acute toxicity of hydrogen peroxide. Valid prolonged toxicity studies were performed in Daphnia magna (NOEC of 0.63 mg/L) and in the marine diatom Skeletonema costatum (NOEC of 0.63 mg/L) indicating that there is no significant difference in the sensitivity of these species to the aquatic toxicity of hydrogen peroxide. The PNEC aqua for freshwater and marine organisms can be derived from the available data by applying an assessment factor of 50. The resulting PNEC aqua is 0.0126 mg/L. A valid respiration inhibition test with hydrogen peroxide using activated sludge from a primarily domestic wastewater treatment plant resulted in an EC50 value of 466 mg/L determined for an incubation duration of 30 minutes. The respiration inhibition was reversible in the test. An assessment factor of 100 is applied to calculate the PNEC STP of 4.66 mg/L.