1H-Isoindol-1-one, 2,3-dihydro-3,3-bis(4-hydroxyphenyl)-2-phenyl-

Hydrolysis

Description of key information

PPP-BP was found to be hydrolytically stable at pH 4, pH 7, and pH 9, as defined by OECD Guideline 111 (OECD, 2002), i.e., less than 10 % loss of PPP-BP was observed after heating for 5.7 days, indicating that the hydrolytic half-life of PPP-BP at these pHs was greater than 1 year at 25°C.

Key value for chemical safety assessment

Half-life for hydrolysis:

1 yr

at the temperature of:

25 °C

Additional information

Based on the HPLC-UV analytical results, PPP-BP was found to be hydrolytically stable at pH 4, pH 7, and pH 9, as defined by OECD Guideline 111 (OECD, 2002). As this indicated less than 10 % loss of PPP-BP after heating for 5.7 days, the hydrolytic half-life of PPP-BP at these pHs can be considered to be greater than 1 year at 25°C.