Registration Dossier

Administrative data

Endpoint:
health surveillance data
Type of information:
other: surveillance
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: no data on exposure time

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Study type:
health record from industry
Test guideline
Qualifier:
according to
Guideline:
other: german Gefahrstoffverordnung §16(2)
Principles of method if other than guideline:
Occupational medical surveillance
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
(no further data)

Method

Details on study design:
medical examination of the staff includes e.g. medical history, physical examination, lung function, ECG/Ergometry, vision testing, audiometry, laboratory examinations of blood and urine
biomonitoring: determination of cresols in urine of workers

Results and discussion

Results:
see section: remarks on results including tables and figures

Any other information on results incl. tables

The results of the measurements show that the concentration of cresols in the air on workplaces fall below the OEL

The maximum cresol concentration from 2003 to 2008 was 0.9 mg/m³.

Occupational medical surveillance did not reveal any health effects like irritaion of the skin, mucosa membranes or upper respiratory tract which could be derived to be from a possible cresol exposure at workplace.

Biomonitoring showed that in case of routine handling of cresols with required protection devices cresol concentrations were in all cased below the limiting value.

Applicant's summary and conclusion

Executive summary:

Occupational medical surveillance of a plant in Germany did not report of complaints from irritational effects from workers. The maximal concentration in the air was 0.9 mg/m³ and is regarded to be the NAEC (Currenta 2008)