Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
02 March 2015-19 June 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP-compliant study in accordance with EC A.4, OECD 104 and EPA OPPTS 830.7950.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
(2009)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
(2006)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7950 (Vapor Pressure)
Version / remarks:
(1996)
Deviations:
no
GLP compliance:
yes
Type of method:
other: Effusion method: isothermal thermogravimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
3-[3-(1,1,1,3,5,5,5-heptamethyltrisiloxan-3-yl)propoxy]propane-1,2-diol
EC Number:
807-413-2
Cas Number:
70280-68-1
Molecular formula:
C13H34O5Si3
IUPAC Name:
3-[3-(1,1,1,3,5,5,5-heptamethyltrisiloxan-3-yl)propoxy]propane-1,2-diol
Test material form:
other: Liquid
Details on test material:
- Name (as cited in study report): X-22-1927
- Appearance: clear light yellow liquid
- Storage conditions: at room temperature

Results and discussion

Vapour pressureopen allclose all
Temp.:
20 °C
Vapour pressure:
0.22 - 0.34 Pa
Temp.:
25 °C
Vapour pressure:
0.35 - 0.54 Pa

Any other information on results incl. tables

The log PT values of the test substance at 20°C were calculated to be -0.47, -0.63 and -0.67 for Experiment 1, 2 and 3, respectively.

The vapour pressures (PT) at 20°C were calculated to be 0.34, 0.24 and 0.22 for Experiment 1, 2 and 3, respectively.

The log PT values of the test substance at 25°C were calculated to be -0.27, -0.42 and -0.46 for Experiment 1, 2 and 3, respectively.

The vapour pressures (PT) at 25°C were calculated to be 0.54, 0.38 and 0.35 for Experiment 1, 2 and 3, respectively.

Table: Results of the isothermal TGA analysis

 

Experiment

Temperature
[°C]

Weight loss
[µg/min]

νT
[g/cm2/h]

log νT

log PT

PT
[Pa]

 

 

 

 

 

 

 

1

70

10.69

1.28 E-03

-2.89

1.26

18

 

80

19.69

2.35 E-03

-2.63

1.57

38

 

90

32.18

3.84 E-03

-2.42

1.82

67

 

 

 

 

 

 

 

2

70

8.676

1.04 E-03

-2.98

1.16

14

 

80

16.45

1.96 E-03

-2.71

1.48

30

 

90

27.01

3.22 E-03

-2.49

1.74

54

 

 

 

 

 

 

 

3

70

8.441

1.01 E-03

-3.00

1.14

14

 

80

16.32

1.95 E-03

-2.71

1.48

30

 

90

26.74

3.19 E-03

-2.50

1.73

54

 

 

 

 

 

 

 

Applicant's summary and conclusion

Conclusions:
In a GLP-compliant study in accordance with EC A.4, OECD 104 and EPA OPPTS 830.7950 using the isothermal thermogravimetric effusion method, the vapour pressure of X-22-1927 at 25°C has been determined to be 0.35 - 0.54 Pa (0.22 - 0.34 Pa at 20°C).