Registration Dossier
Registration Dossier
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EC number: 203-450-8 | CAS number: 106-99-0
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
In accordance with REACH Annexes VII and VIII column 2 adaptation, studies on skin sensitisation do not need to be conducted as the substance is flammable in air at room temperature. No studies have been conducted on skin sensitisation with 1,3-butadiene but there are no indications from repeat dose studies that 1,3-butadiene causes skin sensitisation.
Short description of key information:
There are no data on skin sensitisation and no indications that 1,3-butadiene is a skin sensitiser. Studies on skin sensitisation do not need to be conducted as the substance is a flammable gas at room temperature.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Additional information:
No studies have been conducted on respiratory sensitisation with 1,3-butadiene but there are no indications that 1,3-butadiene is a respiratory sensitizer.
Short description of key information:
No studies have been conducted but there are no data to indicate that 1,3-butadiene is a respiratory sensitizer.
Justification for classification or non-classification
There is no indication that 1,3-butadiene causes skin or respiratory sensitisation and therefore, 1,3-butadiene does not warrant classification under Dir 67/548/EEC or GHS/CLP.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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