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EC number: 203-450-8 | CAS number: 106-99-0
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
As 1,3-butadiene is a gas at standard temperature and pressure conducting a standard ready biodegradability test is technically difficult, and based on exposure estimates the test may not be relevant.
In the absence of a standard study the use of a QSAR model to predict the biodegradability of 1,3-butadiene is an appropriate technique to use as part of a weight of evidence approach to fulfil this endpoint requirement. The use of Biowin is appropriate for 1,3-butadiene as this compound falls within the applicability domains of this model. Results from QSAR models show that it is expected that 1,3 -butadiene is rapidly and potentially readily biodegradable. The results from the Biowin model do not indicate that 1,3-butadiene would be expected to be persistent.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
An OECD TG 301D closed bottle test (MITI, 2001) reported 0 - 4% biodegradation over 28 days. We have been unable to obtain a copy of the original report in order to assess its reliability.
In addition, various researchers have isolated microorganisms that are capable of metabolising 1,3-butadiene. One group (Houet al., 1983) demonstrated that microorganisms can biodegrade 1,3-butadiene under aerobic conditions, however, the study did not follow a standard test guideline for ready biodegradability. This results add to the weight of evidence that 1,3-butadiene has the potential to biodegrade if released to the environment.
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