Registration Dossier
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EC number: 200-659-6 | CAS number: 67-56-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
With high probability acutely not harmful to aquatic invertebrates.
Key value for chemical safety assessment
Additional information
Valid information from acute toxicity testing with Daphnia magna according to OECD guideline 202 is available (Dom et al., 2012). At test termination after 96 h an EC50 of 18260 mg/L was determined.
In a reliable supporting standard static test with Daphnia magna no adverse effects were reported at 10000 mg/L after 48-h exposure (Kuehn, 1989). Toxicity values well above 10000 mg/L reported also for Daphnia magna in other studies support this finding: 22200 mg/L (EC50, 48h) (Rossini and Ronco 1996), 20803 mg/L (EC50, 24h) (Lilius et al. 1995), and 22910 mg/L (LC50, 24h) (Reiff 1976). Aditionally short-term toxicity data are available from tests conducted with other test organism: Mytilus edulis, LC50 (96h) = 15900 mg/L (Helmstetter et al. 1996) and Moina micrura, LC50 (96h) = 4820 mg/L. Although the lowest toxicity was reported for Moina micrura, the study is considered less relevant due to poor documentation on test procedures and conditions. Nevertheless the LC50 -value supports the indication for very low acute toxicity of methanol towards invertebrates.
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