Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Study was given a Klimish score 4 according to OECD SIDS document (2002) for sodium hydroxide on following basis: original reference not available

Data source

Reference
Reference Type:
other:
Title:
No title available
Author:
Sax
Year:
1984
Bibliographic source:
cited in: Martin FM, Report EPA/600/8-88/081 Order-No. PB88-231949, 1988

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Sodium hydroxide
EC Number:
215-185-5
EC Name:
Sodium hydroxide
Cas Number:
1310-73-2
Molecular formula:
HNaO
IUPAC Name:
sodium hydroxide
Details on test material:
- Name of test material (as cited in study report): sodium hydroxide

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
40 mg/kg bw

Applicant's summary and conclusion