Registration Dossier

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

One reliable (Klimisch 1, guideline- and GLP-compliant) study addresses the long-term toxicity of terephthalic acid to freshwater invertebrates.   
In this study (Government of Japan, Ministry of the Environment, 2003c), Daphnia magna were exposed to high purity TPA (free acid), dosed from a stock solution prepared with DMSO, at a concentration intended to approximate to TPA's aqueous solubility limit. No toxicity was observed under these test conditions:
D. magna 21 -d NOEC (semi-static): 19.5 mg TPA/L.
This endpoint is a mean measured value and represents the maximum limit concentration achievable under the test conditions.
Terephthalic acid exhibits low long-term toxicity to aquatic invertebrates.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
19.5 mg/L

Additional information