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Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Cross-reference
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1975
Report date:
1975

Materials and methods

GLP compliance:
no
Limit test:
no

Test material

Constituent 1
Reference substance name:
MCTR-1-75
IUPAC Name:
MCTR-1-75
Details on test material:
- Name of test material (as cited in study report): MCTR 1-75 identified by hand as 85% phosphoric acid

Test animals

Species:
rabbit
Strain:
New Zealand White
Sex:
not specified

Administration / exposure

Duration of exposure:
24 hours
Doses:
2 g/kg BW
No. of animals per sex per dose:
12 animals
Control animals:
no

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
other: Dose level
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.

Any other information on results incl. tables

Results: New Zealand albino rabbits, when exposed dermally to MCTR 1-75 at a dose level of 2.0 g/kg bw, produced severe eschar formation, but no mortality.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information 85% phosphoric acid Criteria used for interpretation of results: expert judgment
Conclusions:
The substance MCTR1-75 identified as 85% phosphoric acid produce severe eschar but no death at a dose of 2 g/kg bw.